Rytis Prekeris Lab

 

 

 

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2024

Hoffman, H.K. and Prekeris, R. (2024) HOPS-dependent lysosomal function controls Rab19 availability for ciliogenesis in polarized epithelial cells. Journal of Cell Science. 137(5):jcs261047. PMID:37665101

Ceglowski, J., Hoffman, H.K., Neumann, A., Hoff, K.J., McCurdy, B.L., Moore, J.K., and Prekeris, R. (2023) TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells. EMBO Reports. In Press. PMID:38177908

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2023

Jewett, C.E., McCurdy, B.L., O’Toole, E.T., Stemm-Wolf, A.J., Lin, C.H., Olsen, V., Martin, W. Reinholdt, L., Espinosa, J.M., Sullivan, K.D., Macklin, W.B., Prekeris, R., and Person, C.G. (2023) Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development. eLife. 12:e78202, PMID: 36656118

 

Lencer, E., Rains, A., Binne, E., Prekeris, R., and Artinger, K. (2023) Mutations in cdon and boc affect trunk neural crest cell migration and slow-twitch muscle development in zebrafish. Development. 150(14):dev201304. PMID: 37390228

 

Farmer, T., Vaeth, K.F., Han, K.J., Goering, R., Taliaferro, J.M., and Prekeris, R. (2023) The Role of Midbody-Associated mRNAs in Regulating Abscission. Journal of Cell Biology. 222(12):e202306123. PMID:37922419

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​Neumann, A., and Prekeris, R. (2023) A Rab-bit hole: Rab40 GTPases as new regulators of the actin cytoskeleton and cell migration. Frontiers in Cell and Developmental Biology. doi: 10.3389/fcell.2023.1268922. PMID:37736498

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2022

Duncan, E.D., Han, K.J., Trout M.A. and Prekeris, R. (2022) Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration. Journal of Cell Biology. 221(4):e202107114. PMID: 35293963

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Han, K.J., Mikalayeva, V., Gerber, S.A., Kettenbach, A.N., Skeberdis, V.A., and Prekeris, R. (2022) Rab40c regulates Focal Adhesions and PP6 activity by controlling ANKRD28 ubiquitylation. Life Science Alliance. In Press. PMID: 35512830

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Farmer, T., and Prekeris, R. (2022) New signaling kid on the block: The role of the post-mitotic midbody in polarity, stemness, and proliferation. Molecular Biology of the Cell. 33(3), PMID:35179994

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Hoffman, H.K. and Prekeris, R. (2022) pathways of ciliogenesis and regulation by actin cytoskeleton. Journal of Cell Science. In Press. PMID: 35575063

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2021

Gibieza, P., Peterman, E., Hoffman, H.K., Van Engeleburg, S., Skeberdis, V.A., and Prekeris, R. (2021) Rab14/MACF2 complex regulates endosomal targeting during cytokinesis. Molecular Biology of the Cell. In Press.

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Jewett, C.E., Soh, A.W.J., Lin, C.H., Lencer, E., Westlake, C.J., Pearson, C.G., and Prekeris, R. (2021) Rab19 directs cortical remodeling and membrane growth for primary ciliogenesis. Developmental Cell. 56(3):325-340.

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Linklater, E.S., Duncan, E.D., Han, K.J., Kaupinis, A., Valius, M., Lyons, T.R. and Prekeris, R. (2021) Rab40/Cullin5 complex regulate EPLIN and actin cytoskeleton dynamics during cell migration and invasion. Journal of Cell Biology. In Press.

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2020

Peterman, E., Valius, M., and Prekeris, R. (2020) CLICK4 is a cytokinesis cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. Journal of Cell Science. 133(9). PMID: 32184265.

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Jewett, C.E., Appel, B.H., and Prekeris, R. (2020) The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development. Biology Open. In Press.

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2019

 Peterman, E., Gibieza, P., Schafer, J., Skeberdis, A., Kaupinis, A., Valius, M., Heiligenstein, X., Hurbain, I., Raposo, G., and Prekeris, R. (2019) The Post-Abscission Midbody is an Intracellular Signaling Organelle that Regulates Cell Proliferation. Nature Communications. 18;10(1):318. PMID: 31320617

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Peterman, E., and Prekeris, R. (2019) The post mitotic midbody: Regulating polarity, stemless, and proliferation. Journal of Cell Biology. 218(12):3903-3911. PMID: 31690620

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